The PROline from Ultrasone tends to be very sharp and sibilant, with it all culminating in the PRO 900 / 2900 which is undoubtedly the most unpleasant hifi headphone I've ever heard. Basically the headphone equivalent of an LRAD sound cannon. It has a cult following because it works semi-well with heavy synthesizer music.
The PRO 450 and 550 have some fans, but I never really felt compelled to listen beyond a cursory few minutes. I haven't heard the PRO 2500, but saying "it's the best of the PROline" is like saying "genital warts are the best venereal disease" in my opinion.
The HFI line is much more listenable. I've had the HFI-2200 (same as the HFI-2400 more or less), and it has a warm and pleasant kind of sound. Not technically proficient, but likable. Little warm butter dripping down a stack of pancakes.
Unfortunately that's about it for their lower end models. With Ultrasone it's all about the ridiculous price tags and high-end materials of their top range models. Even then you run into problems.
The Signature line is the best thing they've ever done, and the Signature Pro is the closest Ultrasone will likely get to a reference headphone. Signature DJ is similar but more 'fun' sounding I guess. Utilitarian build quality, moderate comfort (too much clamp), but good isolation.
The Edition line is hit or miss; I actually really like the Edition 7 (same as Ed. 9) and the infamous pariah, the Edition 10. Of course they're stupidly overpriced and the build quality is surprisingly bad in places---like using materials that react to oils in your skin by instantly turning brown---but the Liquid Cobalt + Ed. 10 was shockingly great sounding. The Edition 8 however is just way too sibilant for my liking.
As aside:
Ultrasone's biggest problem in my opinion is their variability; if people think Beyerdynamic offers a grab bag in that sense, Ultrasone is all the more so. I owned three different Edition 8s, and each one sounded progressively more sibilant. Hearing two Edition 9s side-by-side yielded even bigger sonic differences. While most people hear a sonic mess with the Ed. 10s, the one I owned for a while was actually pretty good.
Even the S-logic technology they use is a crapshoot: with some ears it just doesn't work. For those who can hear it though, it's one of Ultrasone's [few] really good strengths. The Edition 10 I owned had such an incredible since of presence, like instruments were really "there" in physical space. Really it was the only reason I held onto it for so long.