I've been using Isoacoustics with my LS50s and a speaker set before. They probably don't work anywhere near as well as speaker stands ...
If you mean speaker stands of the hifi sort, then they are mostly bits of furniture with the added requirement of not resonating. The isoacoustics claim to do more than that.
Off the desktop, I always avoided the issue of speaker stands by using floorstanders. On
the desktop... well, my neck is not that long
I highly recommend getting even a cheap set of studio monitor stands, they make a world of difference. Table reflections usually create a nasty mid suckout. Some studio monitors are actually tuned to compensate for mixing desk reflections, too bad they never advertise which ones.
My speakers are around 12 inches off the desk. First, there is a shelf, about three inches up, on top of which sit things like the pre-amp, monitor, etc, and below which lives various assorted rubbish (yep: some of it probably resonates
. It's a good thing most of my listening is on the headphones) and then there's... two piles of books.
It's a long-standing (no pun intended) tradition with me: If speakers need extra hight, I put books under them. My first ever all-my-own hifi had speakers raised off the floor on London phone directories.
Not pretty of course. Definitely doesn't resonate, though. Books are pretty dense. Who hasn't moved house and thought, "This is a nice big
box, I can put lots of books
in it," and then tried to pick it up? The only thing I ever did worse than that was a big box full of LPs.